Advanced Oncology Certified Nurse Practitioner (AOCNP) Certification Practice Test 2026 - Free AOCNP Practice Questions and Study Guide

The recommended IV push dosage of Dexamethasone for hypersensitivity reactions is indeed 0.5 mg/kg. This dosage is typically used to effectively manage severe allergic reactions, including anaphylaxis, and works by providing anti-inflammatory effects and immunosuppression. Dexamethasone is a potent glucocorticoid that can help mitigate the immune response contributing to hypersensitivity reactions.

Administering 0.5 mg/kg allows for adequate therapeutic levels of the medication to be reached quickly, which is critical in acute situations where immediate intervention is required. The timing and administration route of Dexamethasone are also essential for achieving rapid relief from symptoms. Dexamethasone acts swiftly, making it suitable for intravenous push in emergencies.

Options such as 0.25 mg/kg may not provide a sufficient response for severe hypersensitivity reactions, while higher dosages like 1 mg/kg or 2 mg/kg exceed typical recommendations and may increase the risk for potential adverse effects without offering additional therapeutic benefit in this context.