Advanced Oncology Certified Nurse Practitioner (AOCNP) Certification Practice Test 2026 - Free AOCNP Practice Questions and Study Guide

The most common cause of death in cancer patients that is not directly related to their malignancy is infection. Cancer patients often experience a range of immune system challenges due to the disease process itself, treatments like chemotherapy, and prolonged hospital stays, all of which can lead to immunocompromised states. This increases their susceptibility to infections, which can become severe and life-threatening.

Infections, particularly bacterial infections, can rapidly escalate in these patients, leading to conditions such as sepsis, which is a critical state often resulting in mortality. Therefore, given the complexities associated with cancer treatment and the vulnerability of the patient population, infection stands out as a significant cause of non-malignant mortality among cancer patients.

While organ failure, cardiovascular disease, and thrombosis also present risks to cancer patients, infections are more frequent due to the reasons outlined above. As a result, they represent a crucial area of focus in the management and care of individuals undergoing cancer treatment.