Advanced Oncology Certified Nurse Practitioner (AOCNP) Certification Practice Test 2025 - Free AOCNP Practice Questions and Study Guide

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Which chemotherapy regimen is commonly used for breast cancer?

FOLFOX

AC-T (Doxorubicin and Cyclophosphamide followed by Taxane)

The AC-T regimen, which consists of Doxorubicin (A) and Cyclophosphamide (C) followed by a Taxane, is a commonly used chemotherapy treatment for breast cancer. This combination has been shown to be effective in breast cancer management, especially in early-stage and some advanced-stage cases.

Doxorubicin, an anthracycline, works by interfering with the cancer cell's DNA, thereby inhibiting its ability to proliferate. Cyclophosphamide is an alkylating agent that also impacts DNA function, enhancing the effectiveness of the regimen. The subsequent addition of a Taxane, such as Paclitaxel or Docetaxel, further targets breast cancer cells by stabilizing the microtubules, causing cell cycle arrest and apoptosis. This comprehensive approach is particularly beneficial for patients with hormone receptor-positive tumors or those at high risk for recurrence.

The other regimens listed, while effective for other cancers, are not standard in the treatment of breast cancer. FOLFOX is primarily used for colorectal cancer. BEACOPP is utilized in the treatment of Hodgkin lymphoma, and CHOP is typically used for non-Hodgkin lymphoma. Each of these regimens targets distinct cancer types with

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BEACOPP

CHOP

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